In Japan, the Ministry of Labor (MOL) is responsible for the safety and health of workers. Under the Ordinance on Prevention of Hazards due to Specified Chemical Substances, derived from the Industrial and Health Law, the Ministry has listed nickel carbonyl as a hazardous substance. Employers are required to attend courses on the proper installation of ventilation systems to assure that nickel carbonyl concentrations do not exceed 0.007 mg Ni/m3.
Although there are no mandated standards for inorganic forms of nickel, the Japan Association of Industrial Health, a non-governmental organization, has recommended an OEL (eight-hour TWA) of 1.0 mg Ni/m3 for all forms of inorganic nickel. The Association’s OEL recommendation for nickel carbonyl is the same as the MOL’s.